Naphthylamine

Naphthylamine

SCHEMBL76713

Nc1ccc2ccccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
HSD17B10 Q99714 3/20 1.00
CYP3A4 P08684 3/20 1.00
CASP1 P29466 3/20 0.84
TDP1 Q9NUW8 2/20 0.84
ALOX15 P16050 1/20 0.84
CASP7 P55210 1/20 0.84
HBB P68871 1/20 0.84
HIF1A Q16665 1/20 0.84
KDM4E B2RXH2 2/20 0.56
MAPT P10636 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
HTR3A P46098 1/20 0.54
PLAU P00749 2/20 0.48
HTT P42858 2/20 0.48
TP53 P04637 1/20 0.48
HSP90AA1 P07900 1/20 0.48
HSP90AB1 P08238 1/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL3935606 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4CASP1TDP1
Naphthylamine SCHEMBL29394720 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4CASP1TDP1
Anthracene SCHEMBL28853790 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10CYP3A4CASP1TDP1
Naphthylamine SCHEMBL7454282 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10CYP3A4CASP1TDP1
Naphthylamine SCHEMBL1467866 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10CYP3A4CASP1TDP1
Naphthylamine SCHEMBL30278502 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10CYP3A4CASP1TDP1
Naphthylamine SCHEMBL28469421 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10CYP3A4CASP1TDP1
Naphthylamine SCHEMBL11381558 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10CYP3A4CASP1TDP1
Naphthylamine SCHEMBL8440070 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10CYP3A4CASP1TDP1
Naphthylamine SCHEMBL11381552 0.97 ALDH1A1 (0.94) ALDH1A1HSD17B10CYP3A4CASP1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15861 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117902997-B Amine antioxidant and preparation method and application thereof PETROCHINA COMPANY LIMITED (CN) 2026-05-26 CN claimed
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
CN-122037054-A Polymer, patterning composition, patterning film, patterning method and application thereof 珠海基石科技有限公司 2026-05-15 CN claimed
CN-122043864-A Patterning composition, patterning film, patterning method and application thereof 珠海基石科技有限公司 2026-05-15 CN claimed
US-12624144-B2 Method for preparing hollow covalent organic framework materials ZHEJIANG UNIVERSITY (CN) 2026-05-12 US claimed
CN-122012066-A Composite acid for acidification and preparation method thereof 胜利油田华滨化工有限责任公司 2026-05-12 CN claimed
WO-2026090321-A1 TREATMENT OF CANCER WITH A KRAS INHIBITOR ALTEROME THERAPEUTICS, INC. (US) 2026-04-30 WO claimed
US-12575601-B2 Reduction of amines and nitrosamines in cigarette smoke vapors through a filter functionalized with olive tree polyphenols MAGI'S LAB SRL (IT) 2026-03-17 US claimed
US-12544025-B2 Determining a biological tissue structural marker for diagnosis of a disease Arion Diagnostics, Inc. (US) 2026-02-10 US claimed
US-12466842-B2 Substituted pyrido [4,3-d]pyrimidines as KRAS modulators ALTEROME THERAPEUTICS, INC. (US) 2025-11-11 US claimed
US-4141845-A TETRAESTER OF PENTAERYTHRITOL, ARYLAMINES, PHOSPHATE ESTERS AND S-ARYL-2-MERCAPTOBENZOTHIAZOLE OXIDATION RESISTANCE TEXACO INC. (US) 1979-02-27 US claimed
EP-0000634-A1 Process for the manufacture of naphthylamine sulphonic acids The Clayton Aniline Company Limited (GB) 1979-02-07 EP claimed
US-4125400-A Agricultural spray oil containing oxidation inhibitors TEXACO TRINIDAD, INC. (TT) 1978-11-14 US claimed
US-4124513-A PENTAERYTHRITOL, CARBOXYLIC ACIDS, AMINES, ANTHRAQUINONES, PHOSPHATE ESTERS, N-ALKYL-BENZOTHIAZOLE-2-THIONE TEXACO INC. (US) 1978-11-07 US claimed
US-4118349-A Process for the manufacture of polystyrene latex compounds BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1978-10-03 US claimed
US-4096078-A LUBRICATING OILS, ESTER BASED TEXACO INC. (US) 1978-06-20 US claimed
US-4060552-A FROM B-NAPHTHOL AND P-PHENYLENEDIAMINE, BORIC OXIDE THE B. F. GOODRICH COMPANY (US) 1977-11-29 US claimed
US-4049457-A WITH AN ORGANIC ACID BARD LABORATORIES, INC. (US) 1977-09-20 US claimed
US-3972878-A Method for preparing azines and hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-03 US claimed
US-3936307-A Light and heat sensitive composition for producing a colored transfer complex image MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1976-02-03 US claimed