Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563578 | 0.86 | ITGB3 (0.37) | PLAUITGB3ITGA2BF2 | |
| SCHEMBL6563915 | 0.85 | ITGB3 (0.35) | PLAUITGB3ITGA2BHPNKLK1 | |
| SCHEMBL6565274 | 0.84 | ITGB3 (0.39) | PLAUITGB3ITGA2BF2 | |
| SCHEMBL6565190 | 0.83 | MRGPRX1 (0.33) | PLAUITGB3ITGA2BHPNKLK1 | |
| SCHEMBL7672376 | 0.83 | ITGB3 (0.32) | PLAUITGB3ITGA2BKLK1KLK5 | |
| SCHEMBL6565916 | 0.83 | ITGB3 (0.35) | PLAUITGB3ITGA2BHPNKLK1 | |
| SCHEMBL6562499 | 0.82 | ITGB3 (0.34) | PLAUITGB3ITGA2BHPNKLK1 | |
| SCHEMBL6562071 | 0.82 | F10 (0.34) | PLAUITGB3ITGA2BHPNKLK1 | |
| SCHEMBL6563611 | 0.82 | ITGB3 (0.38) | PLAUITGB3ITGA2BF2 | |
| SCHEMBL4250003 | 0.82 | ITGB3 (0.37) | PLAUITGB3ITGA2BHPNKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |