Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 10/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 10/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168858 | 0.94 | AGTR1 (0.53) | AGTR1AGTR2RAB9ATP53POLB | |
| SCHEMBL169971 | 0.89 | KDM4E (0.53) | AGTR1AGTR2PDE2A | |
| SCHEMBL6171683 | 0.88 | AGTR1 (0.78) | AGTR1AGTR2RAB9ATP53POLB | |
| SCHEMBL7669972 | 0.88 | AGTR1 (0.52) | AGTR1AGTR2PDE2A | |
| SCHEMBL7671692 | 0.88 | AGTR1 (0.58) | AGTR1AGTR2RAB9A | |
| SCHEMBL6169187 | 0.86 | AGTR1 (0.52) | AGTR1AGTR2PDE2A | |
| SCHEMBL6168445 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2RAB9AMEN1KMT2A | |
| SCHEMBL7668569 | 0.82 | TDP1 (0.52) | AGTR1AGTR2TP53MEN1KMT2A | |
| SCHEMBL7676515 | 0.82 | PPARG (0.55) | AGTR1AGTR2TP53POLBPDE2A | |
| SCHEMBL6169463 | 0.82 | MEN1 (0.50) | RAB9ATP53POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6352985-B1 | CARDIOVASCULAR DISORDERS OR GASTROINTESTINAL DISORDERS, DIABETES (TYPE II DIABETES), DIABETIC COMPLICATIONS METHOD FOR LOWERING THE BLOOD SUGAR LEVEL OF A PATIENT, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| EP-1132087-A1 | REMEDIES FOR POLYCYSTIC OVARY SYNDROME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-6166219-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0882718-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |