Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | GABRP | O00591 | 2/20 | 0.61 |
| ▸ | GABRD | O14764 | 2/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.61 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.61 |
| ▸ | GABRE | P78334 | 2/20 | 0.61 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.61 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.61 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.61 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | TACR1 | P25103 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671347 | 0.88 | KMT2A (0.68) | POLBGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7669404 | 0.86 | POLB (0.65) | POLBCTDSP1KMT2ATACR1KDM4E | |
| SCHEMBL7838780 | 0.85 | POLB (0.73) | POLBCTDSP1KMT2ATACR1KDM4E | |
| SCHEMBL7677893 | 0.85 | POLB (0.64) | POLBCTDSP1KMT2ATACR1KDM4E | |
| SCHEMBL7673231 | 0.85 | POLB (0.64) | POLBCTDSP1KMT2ATACR1KDM4E | |
| SCHEMBL7677992 | 0.85 | POLB (0.64) | POLBGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7674750 | 0.84 | POLB (0.59) | POLBGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7850770 | 0.83 | POLB (0.61) | POLBCTDSP1KMT2ATACR1KDM4E | |
| SCHEMBL7678202 | 0.83 | POLB (0.66) | POLBGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7673280 | 0.82 | POLB (0.62) | POLBCTDSP1KMT2ATACR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |