Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865997 | 0.93 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9868733 | 0.89 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9573578 | 0.86 | CCKBR (0.79) | CCKBR | |
| SCHEMBL9866502 | 0.84 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9867257 | 0.84 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9866033 | 0.83 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9865215 | 0.83 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9866172 | 0.83 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9596496 | 0.83 | CCKBR (0.71) | CCKBR | |
| SCHEMBL9595792 | 0.83 | CCKBR (0.76) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434364-A2 | Benzodiazepine analogs for treating panic syndrome and for directly inducing analgesia | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | claimed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | claimed |
| US-6492531-B1 | THE INVENTION CONCERNS CHOLECYSTOKININ (CCK) ANTAGONISTS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS. ESPECIALLY USEFUL ARE CCK.SUB.B ANTAGONISTS SUCH AS CI-988. | WARNER-LAMBERT COMPANY | 2002-12-10 | — | — | US | disclosed |
| EP-0729752-A2 | Central cholecystokinin antagonists having pharmaceutical activity | MERCK SHARP & DOHME LTD. (GB) | 1996-09-04 | — | — | EP | disclosed |
| EP-0617621-A4 | CENTRAL CHOLECYSTOKININ ANTAGONISTS HAVING PHARMACEUTICAL ACTIVITY. | MERCK SHARP & DOHME (GB) | 1995-04-05 | — | — | EP | disclosed |
| EP-0617621-A1 | CENTRAL CHOLECYSTOKININ ANTAGONISTS HAVING PHARMACEUTICAL ACTIVITY | MERCK SHARP & DOHME LTD. (GB) | 1994-10-05 | — | — | EP | disclosed |
| WO-1993012791-A1 | CENTRAL CHOLECYSTOKININ ANTAGONISTS HAVING PHARMACEUTICAL ACTIVITY | MERCK SHARP & DOHME LIMITED (GB) | 1993-07-08 | — | — | WO | disclosed |
| WO-1993012817-A1 | THERAPEUTIC COMBINATIONS USEFUL IN THE TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE | WARNER-LAMBERT COMPANY (US) | 1993-07-08 | — | — | WO | disclosed |
| EP-0434364-A2 | Benzodiazepine analogs for treating panic syndrome and for directly inducing analgesia | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |
| US-4820834-A | Benzodiazepine analogs | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0274324-A1 | Process for the preparation of thienylethyl amines, and dithienylethyl amines so obtained | SANOFI (FR) | 1988-07-13 | — | — | EP | disclosed |