Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672406 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2ACHRM5 | |
| SCHEMBL17039295 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ACHRM5 | |
| SCHEMBL1532835 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1KMT2ACHRM5 | |
| SCHEMBL31509781 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ACHRM5 | |
| SCHEMBL18482672 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ACHRM5 | |
| SCHEMBL18221641 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ACHRM5 | |
| SCHEMBL5700291 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ACHRM5 | |
| SCHEMBL827241 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ACHRM5 | |
| SCHEMBL5260389 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ACHRM5 | |
| SCHEMBL30351276 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2ACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |