Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672459 | 1.00 | MAOA (0.37) | MAOAMAOBCA1MGLLALDH1A1 | |
| SCHEMBL9180238 | 0.92 | MAOA (0.43) | MAOAMAOB | |
| SCHEMBL9180243 | 0.92 | MAOA (0.43) | MAOAMAOB | |
| SCHEMBL10786744 | 0.87 | MAOA (0.44) | MAOAMAOBALDH1A1LMNAGAA | |
| SCHEMBL10786736 | 0.87 | MAOA (0.44) | MAOAMAOBALDH1A1LMNAGAA | |
| SCHEMBL10786740 | 0.87 | MAOA (0.44) | MAOAMAOBALDH1A1LMNAGAA | |
| SCHEMBL27909303 | 0.84 | MAOB (0.41) | MAOAMAOBCA1MGLLALDH1A1 | |
| SCHEMBL27909305 | 0.84 | MAOB (0.41) | MAOAMAOBCA1MGLLALDH1A1 | |
| SCHEMBL28007660 | 0.82 | LCK (0.44) | MAOBLMNAMAPT | |
| SCHEMBL28007659 | 0.82 | LCK (0.44) | MAOBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388146-B1 | AROMATIC UNSATURATED NOMONER | SHARP KABUSHIKI KAISHA (JP) | 2002-05-14 | — | — | US | disclosed |