SCHEMBL7672628

SCHEMBL7672628

CC[C@@H]1CCN[C@H]1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 1/20 0.54
ARG1 P05089 5/20 0.53
ARG2 P78540 1/20 0.53
MEN1 O00255 1/20 0.45
BLM P54132 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2033259 1.00 SLC1A2 (0.54) SLC1A2ARG1ARG2MEN1BLM
SCHEMBL5704293 1.00 SLC1A2 (0.54) SLC1A2ARG1ARG2MEN1BLM
SCHEMBL14216687 1.00 SLC1A2 (0.54) SLC1A2ARG1ARG2MEN1BLM
SCHEMBL2033261 1.00 SLC1A2 (0.54) SLC1A2ARG1ARG2MEN1BLM
SCHEMBL2033263 1.00 SLC1A2 (0.54) SLC1A2ARG1ARG2MEN1BLM
Hydrochloric Acid SCHEMBL7748845 0.98 SLC1A2 (0.52) SLC1A2ARG1ARG2MEN1BLM
Hydrochloric Acid SCHEMBL7748836 0.98 SLC1A2 (0.52) SLC1A2ARG1ARG2MEN1BLM
Hydrochloric Acid SCHEMBL7748843 0.98 SLC1A2 (0.52) SLC1A2ARG1ARG2MEN1BLM
SCHEMBL16056702 0.88 ARG1 (0.59) SLC1A2ARG1ARG2MEN1BLM
Hydrochloric Acid SCHEMBL7809370 0.86 ARG1 (0.43) SLC1A2ARG1ARG2MEN1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6350882-B1 REACTION OF PROLINE SALT AND ALKALI HALIDE WITH UNSATURATED ALDEHYDE, MIXING, ACIDIFICATION AND BASIFICATION MERCK & CO., INC. 2002-02-26 US claimed
US-6350882-B1 REACTION OF PROLINE SALT AND ALKALI HALIDE WITH UNSATURATED ALDEHYDE, MIXING, ACIDIFICATION AND BASIFICATION MERCK & CO., INC. 2002-02-26 US disclosed