SCHEMBL7672671

SCHEMBL7672671

C=CCOC(=O)c1cc(C)ccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.56
KLF10 Q13118 1/20 0.52
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
CA12 O43570 2/20 0.51
CA7 P43166 2/20 0.51
CA9 Q16790 2/20 0.51
CA14 Q9ULX7 2/20 0.51
CSNK2A1 P68400 1/20 0.50
ALDH1A1 P00352 2/20 0.49
HSD17B10 Q99714 2/20 0.49
TSHR P16473 1/20 0.49
KDM4E B2RXH2 3/20 0.47
TP53 P04637 1/20 0.47
HPGD P15428 1/20 0.47
APP P05067 1/20 0.44
KMT2A Q03164 3/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 2/20 0.41
LMNA P02545 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7647241 0.88 CYP3A4 (0.56) CYP3A4CA1CA2CA12CA7
SCHEMBL11061923 0.87 CYP3A4 (0.64) CYP3A4CA1CA2CA12CA7
SCHEMBL22472109 0.87 CYP3A4 (0.56) CYP3A4KLF10CA1CA2CA12
SCHEMBL2966217 0.84 CA12 (0.63) CYP3A4CA1CA2CA12CA7
SCHEMBL8786921 0.83 ALDH1A1 (0.63) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL1641611 0.82 CA12 (0.74) KLF10CA1CA2CA12CA7
SCHEMBL788648 0.81 CYP3A4 (0.63) CYP3A4CA1CA2CA12CA7
SCHEMBL24728384 0.81 CYP3A4 (0.56) CYP3A4CA1CA2CA12CA7
SCHEMBL11847851 0.81 CYP3A4 (0.56) CYP3A4CA1CA2CA12CA7
SCHEMBL31020227 0.81 CYP3A4 (0.56) CYP3A4CA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0920413-B1 BORONIC COMPOUND COMPLEXING REAGENTS AND COMPLEXES PROLINX INC (US) 2002-11-13 EP claimed