SCHEMBL7672809

SCHEMBL7672809

CCCCCNc1ccc[c]c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.39
ABL1 P00519 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 2/20 0.38
RAB9A P51151 1/20 0.38
NR4A2 P43354 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
KCNH3 Q9ULD8 1/20 0.36
CNR2 P34972 4/20 0.36
CNR1 P21554 1/20 0.35
HRH4 Q9H3N8 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
TLR8 Q9NR97 1/20 0.35
CISD1 Q9NZ45 1/20 0.35
SIGMAR1 Q99720 1/20 0.34
CHRM2 P08172 1/20 0.34
GPR84 Q9NQS5 1/20 0.34
MEN1 O00255 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27671342 0.80 IDO1 (0.35) SMN1; SMN2RAB9AMEN1TSHRHTT
SCHEMBL1724131 0.76 L3MBTL1 (0.51) L3MBTL1SMN1; SMN2KDM4ERAB9ANPSR1
SCHEMBL30174089 0.74 L3MBTL1 (0.54) L3MBTL1SMN1; SMN2NPSR1KCNH3CNR2
SCHEMBL8535750 0.74 L3MBTL1 (0.54) L3MBTL1SMN1; SMN2NPSR1KCNH3CNR2
SCHEMBL11266453 0.74 L3MBTL1 (0.54) L3MBTL1SMN1; SMN2NPSR1KCNH3CNR2
SCHEMBL11266466 0.74 L3MBTL1 (0.54) L3MBTL1SMN1; SMN2NPSR1KCNH3CNR2
SCHEMBL28732815 0.74 ABL1 (0.49) L3MBTL1ABL1SMN1; SMN2KDM4ENR4A2
SCHEMBL30069272 0.71 CNR1 (0.57) L3MBTL1SMN1; SMN2KDM4ENR4A2NPSR1
SCHEMBL1926387 0.71 L3MBTL1 (0.48) L3MBTL1SMN1; SMN2NPSR1KCNH3CNR2
SCHEMBL3267706 0.71 L3MBTL1 (0.44) L3MBTL1SMN1; SMN2KDM4ENR4A2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6348474-B1 COMPOUNDS AS ANTIDIABETIC AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-02-19 US disclosed