Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667617 | 0.89 | TNKS2 (0.64) | TNKS2ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7670240 | 0.84 | TNKS2 (0.65) | TNKS2ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL31338442 | 0.84 | TNKS2 (0.64) | TNKS2ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL29913510 | 0.79 | TNKS2 (1.00) | TNKS2ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7674927 | 0.79 | TNKS2 (1.00) | TNKS2ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7665294 | 0.78 | ALDH1A1 (1.00) | TNKS2ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL2821455 | 0.78 | TNKS2 (0.72) | TNKS2ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL30257239 | 0.78 | ALDH1A1 (1.00) | TNKS2ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL27925494 | 0.78 | TNKS2 (0.72) | TNKS2ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL27925475 | 0.78 | TNKS2 (0.72) | TNKS2ALDH1A1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479499-B1 | INHIBITORS OF TUBULIN POLYMERIZATION | NATIONAL SCIENCE COUNCIL (TW) | 2002-11-12 | — | — | US | disclosed |