Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 16/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674091 | 0.91 | OPRD1 (0.67) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7667725 | 0.89 | OPRD1 (0.73) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7665785 | 0.88 | OPRD1 (0.64) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7665746 | 0.86 | OPRD1 (0.64) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7667049 | 0.81 | OPRD1 (0.68) | OPRD1OPRK1OPRM1HRH3 | |
| SCHEMBL7673873 | 0.81 | OPRD1 (0.70) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7668357 | 0.81 | OPRD1 (0.69) | OPRD1OPRK1OPRM1HRH3 | |
| SCHEMBL7660942 | 0.81 | OPRD1 (0.74) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7665640 | 0.81 | OPRD1 (0.75) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7665763 | 0.80 | OPRD1 (0.67) | OPRD1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444679-B1 | NEUROLOGICAL AND GASTROINTESTINAL DISORDERS; DELTA OPIOID LIGANDS OR OPIOID RECEPTORS | PFIZER INC | 2002-09-03 | — | — | US | disclosed |
| EP-1038872-A1 | 4-Phenyl-4-heteroarylpiperdine derivatives as opioid receptor ligands | Pfizer Products Inc. (US) | 2000-09-27 | — | — | EP | disclosed |