Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 5/20 | 0.68 |
| ▸ | ADH1A | P07327 | 5/20 | 0.68 |
| ▸ | ADH7 | P40394 | 4/20 | 0.68 |
| ▸ | ADH1C | P00326 | 4/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.59 |
| ▸ | ADH4 | P08319 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26602 | 0.82 | — | — | |
| SCHEMBL27768502 | 0.80 | — | — | |
| SCHEMBL27768518 | 0.80 | — | — | |
| SCHEMBL5254384 | 0.78 | ADH1B (0.90) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL9391 | 0.78 | — | — | |
| SCHEMBL1963312 | 0.76 | ADH1B (0.85) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL987947 | 0.76 | EPHX1 (0.44) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL302735 | 0.75 | EPHX1 (1.00) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL4879688 | 0.75 | EPHX1 (1.00) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL145544 | 0.75 | EPHX1 (1.00) | ADH1BADH1AADH7ADH1CEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214331-A2 | 2-AZAPURINE COMPOUNDS AND THEIR USE | Roche Diagnostics GmbH (DE) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001016149-A2 | 2-AZAPURINE COMPOUNDS AND THEIR USE | ROCHE DIAGNOSTICS GMBH (DE) | 2001-03-08 | — | — | WO | disclosed |
| EP-0778898-A1 | REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES | CHIRON CORPORATION (US) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006950-A9 | REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES | — | 1997-05-09 | — | — | WO | disclosed |
| WO-1996006950-A1 | REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES | CHIRON CORPORATION (US) | 1996-03-07 | — | — | WO | disclosed |