Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 17/20 | 0.87 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.87 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.82 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683691 | 0.91 | OPRD1 (0.83) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7665711 | 0.90 | OPRD1 (0.84) | OPRD1OPRK1OPRM1HDAC6KDR | |
| SCHEMBL7669862 | 0.90 | OPRD1 (1.00) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7666997 | 0.89 | OPRD1 (0.81) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7666983 | 0.88 | OPRD1 (0.80) | OPRD1OPRK1OPRM1 | |
| SCHEMBL8134558 | 0.88 | OPRD1 (0.81) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7666977 | 0.86 | OPRD1 (0.73) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7671663 | 0.85 | OPRD1 (0.75) | OPRD1OPRK1OPRM1 | |
| SCHEMBL8124466 | 0.85 | OPRD1 (0.67) | OPRD1OPRK1OPRM1HDAC6KDM4E | |
| Diethylamine SCHEMBL7672966 | 0.84 | OPRD1 (0.75) | OPRD1OPRK1OPRM1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444679-B1 | NEUROLOGICAL AND GASTROINTESTINAL DISORDERS; DELTA OPIOID LIGANDS OR OPIOID RECEPTORS | PFIZER INC | 2002-09-03 | — | — | US | disclosed |
| EP-1038872-A1 | 4-Phenyl-4-heteroarylpiperdine derivatives as opioid receptor ligands | Pfizer Products Inc. (US) | 2000-09-27 | — | — | EP | disclosed |