SCHEMBL7673965

SCHEMBL7673965

CCC1=Cc2c(-c3cc4ccccc4c4ccccc34)cccc2C1[Zr]

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP11B1 P15538 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27559648 0.88 SLC6A4 (0.33) ALDH1A1HPGDMAPK1L3MBTL1
Hydrochloric Acid SCHEMBL27493411 0.83 ALDH1A1 (0.36) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL27541344 0.81 ALDH1A1 (0.34) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL13822733 0.79 ALDH1A1 (0.33) ALDH1A1HPGDTSHRMAPK1CASP1
Hydrochloric Acid SCHEMBL4658320 0.78 ALDH1A1 (0.32) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL27929393 0.78 ALDH1A1 (0.35) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL27946705 0.78 ALDH1A1 (0.32) ALDH1A1HPGDTSHRMAPK1CASP1
Hydrochloric Acid SCHEMBL4474485 0.78 ALDH1A1 (0.32) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL5952817 0.78 ALDH1A1 (0.32) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL6013799 0.78 ALDH1A1 (0.32) ALDH1A1HPGDTSHRMAPK1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1250365-A2 TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS Basell Polypropylen GmbH (DE) 2002-10-23 EP disclosed
WO-2001048034-A2 TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2001-07-05 WO disclosed