Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674137 | 1.00 | RAB9A (0.43) | RAB9AHCRTR2HCRTR1OPRK1NPC1 | |
| SCHEMBL6099357 | 0.89 | RAB9A (0.42) | RAB9ANPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6099353 | 0.89 | RAB9A (0.42) | RAB9ANPC1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6102018 | 0.87 | KDM4E (0.36) | RAB9AHCRTR2HCRTR1OPRK1NPC1 | |
| SCHEMBL6102022 | 0.87 | KDM4E (0.36) | RAB9AHCRTR2HCRTR1OPRK1NPC1 | |
| SCHEMBL6566910 | 0.86 | KDM4E (0.36) | RAB9AHCRTR2HCRTR1OPRK1NPC1 | |
| SCHEMBL6567869 | 0.86 | KDM4E (0.36) | RAB9AHCRTR2HCRTR1OPRK1NPC1 | |
| SCHEMBL6566914 | 0.86 | KDM4E (0.36) | RAB9AHCRTR2HCRTR1OPRK1NPC1 | |
| SCHEMBL7667546 | 0.86 | KDM4E (0.35) | RAB9AHCRTR2HCRTR1OPRK1NPC1 | |
| SCHEMBL7667547 | 0.86 | KDM4E (0.35) | RAB9AHCRTR2HCRTR1OPRK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486183-B1 | Antivirals | MEDIVIR AB (SE) | 2002-11-26 | — | — | US | disclosed |