Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954367 | 0.77 | LMNA (0.33) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL7672353 | 0.73 | — | — | |
| SCHEMBL7672316 | 0.73 | LMNA (0.39) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL21371585 | 0.72 | LMNA (0.31) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL7672730 | 0.71 | CACNA1F (0.36) | ADRA1A | |
| SCHEMBL7679175 | 0.71 | — | — | |
| SCHEMBL7673878 | 0.70 | SLC6A4 (0.35) | TDP1 | |
| SCHEMBL7678720 | 0.70 | LMNA (0.37) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL6209009 | 0.69 | LMNA (0.50) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL10245268 | 0.69 | LMNA (0.50) | LMNACNR1ADRA1ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017737-A4 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | UNIV CALIFORNIA (US) | 2002-06-26 | — | — | EP | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1017737-A1 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | The Regents of the University of California (US) | 2000-07-12 | — | — | EP | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999011692-A1 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-03-11 | — | — | WO | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| EP-1017737-A4 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | UNIV CALIFORNIA (US) | 2002-06-26 | — | — | EP | disclosed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | disclosed |
| EP-1017737-A1 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | The Regents of the University of California (US) | 2000-07-12 | — | — | EP | disclosed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999011692-A1 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-03-11 | — | — | WO | disclosed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | disclosed |