Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.52 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30775240 | 1.00 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28245824 | 1.00 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL27706517 | 1.00 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28176068 | 1.00 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL11531633 | 1.00 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8455146 | 1.00 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28766385 | 1.00 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL3823038 | 1.00 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28741692 | 0.98 | GPR84 (0.52) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28245065 | 0.98 | GPR84 (0.50) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715822-A | Specific substrates for ALDH isozymes | 高级生物设计公司 | 2019-05-03 | — | — | CN | disclosed |
| US-6380239-B1 | FOR THERAPY OF ARTHRITIS, RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, REPERFUSION INJURY, INFLAMMATORY BOWEL DISEASE, CROHN'S DISEASE, ULCERATIVE COLITIS, SYSTEMIC LUPUS ERYTHREMATOSIS, SCLERODERMA, APHTHOUS ULCERS, ASTHMA | CELGENE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| US-4824865-A | Treatment of skin disorders | LEVER BROTHERS COMPANY (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0232982-A2 | Treatment of skin disorders | UNILEVER PLC (GB) | 1987-08-19 | — | — | EP | disclosed |