Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 14/20 | 0.74 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693851 | 0.95 | PTPN1 (0.80) | PTPN1PTPN22CTSSCTSLCTSB | |
| SCHEMBL7693854 | 0.95 | PTPN1 (0.80) | PTPN1PTPN22CTSSCTSLCTSB | |
| SCHEMBL7671807 | 0.88 | PTPN1 (0.72) | PTPN1PTPN22CTSSCTSLCTSB | |
| SCHEMBL7680706 | 0.87 | PTPN1 (0.83) | PTPN1PTPN22CTSSCTSLCTSB | |
| SCHEMBL7672386 | 0.87 | PTPN1 (0.83) | PTPN1PTPN22CTSSCTSLCTSB | |
| SCHEMBL7798217 | 0.86 | PTPN1 (0.82) | PTPN1PTPN22PSMB1PSMB9PSMB5 | |
| SCHEMBL7676519 | 0.86 | PTPN1 (0.76) | PTPN1PTPN22CTSSCTSLCTSB | |
| SCHEMBL7671723 | 0.85 | PTPN1 (0.86) | PTPN1PTPN22CTSSCTSLCTSB | |
| SCHEMBL7673490 | 0.85 | PTPN1 (0.86) | PTPN1PTPN22CTSSCTSLCTSB | |
| SCHEMBL7672339 | 0.85 | PTPN1 (0.71) | PTPN1PTPN22CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |