Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 16/20 | 0.52 |
| ▸ | ACE | P12821 | 14/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.44 |
| ▸ | CPA1 | P15085 | 8/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565484 | 0.81 | MME (0.67) | MMEACEACE2CPA1LPAR1 | |
| SCHEMBL6897391 | 0.81 | MME (0.47) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL6897389 | 0.81 | MME (0.47) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL6898434 | 0.76 | MME (0.67) | MMEACEACE2CPA1 | |
| SCHEMBL8027331 | 0.75 | MME (0.82) | MMEACEACE2CPA1 | |
| SCHEMBL8027335 | 0.75 | MME (0.82) | MMEACEACE2CPA1 | |
| SCHEMBL7573798 | 0.74 | MME (0.71) | MMEACEACE2CPA1 | |
| SCHEMBL7569072 | 0.74 | MME (0.67) | MMEACEACE2CPA1 | |
| SCHEMBL7569066 | 0.74 | MME (0.67) | MMEACEACE2CPA1 | |
| SCHEMBL7569387 | 0.74 | MME (0.67) | MMEACEACE2CPA1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |