Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 17/20 | 0.47 |
| ▸ | ACE | P12821 | 15/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 12/20 | 0.44 |
| ▸ | CPA1 | P15085 | 11/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897389 | 1.00 | MME (0.47) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL6899397 | 0.89 | L3MBTL1 (0.40) | MMEACEACE2CPA1 | |
| SCHEMBL6899389 | 0.89 | L3MBTL1 (0.40) | MMEACEACE2CPA1 | |
| SCHEMBL7674564 | 0.81 | MME (0.52) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL6895067 | 0.79 | L3MBTL1 (0.43) | MMEACEACE2CPA1 | |
| SCHEMBL6895064 | 0.79 | L3MBTL1 (0.43) | MMEACEACE2CPA1 | |
| SCHEMBL6895453 | 0.77 | MMP2 (0.47) | — | |
| SCHEMBL6895445 | 0.77 | MMP2 (0.47) | — | |
| SCHEMBL6898184 | 0.77 | L3MBTL1 (0.41) | MMEACEACE2CPA1 | |
| SCHEMBL6898179 | 0.77 | L3MBTL1 (0.41) | MMEACEACE2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730784-B2 | AS THERAPEUTIC AGENTS FOR AUTOIMMUNE DISEASES SUCH AS RHEUMATOID ARTHRITIS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-04 | — | — | US | disclosed |
| US-20020198376-A1 | Novel urea derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1072591-A1 | NOVEL UREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198376-A1 | Novel urea derivatives | TNF, CTH, CFH | MME 1516/4885ACE 1063/4885ACE2 1466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.