SCHEMBL767463

SCHEMBL767463

Clc1ccc(I)c(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29588504 1.00
SCHEMBL6181971 0.97 TP53 (0.52)
SCHEMBL5671038 0.97 TP53 (0.52)
Ether SCHEMBL3726510 0.81 TDP1 (0.40)
SCHEMBL29720648 0.77
SCHEMBL1350393 0.77
SCHEMBL79921 0.77
SCHEMBL3538617 0.77 AHR (0.55)
SCHEMBL15823211 0.74 MAOA (0.48)
SCHEMBL25407372 0.72 TP53 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073420-A Preparation method of 2-phenylbenzothiophene derivative 陕西维世诺新材料有限公司 2022-09-20 CN claimed
CN-111097520-A Covalent organic framework material loaded Pd catalyst and preparation method and application thereof 中国科学院广州能源研究所 2020-05-05 CN claimed
EP-0111658-B1 1,3-DIHALOPROPAN-2-OLS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-12-30 EP claimed
US-12630515-B2 Small molecule prostagladin transport inhibitors ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2026-05-19 US disclosed
US-12600725-B2 Selective GRP94 inhibitors and uses thereof MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2026-04-14 US disclosed
EP-4054608-B1 SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS ALBERT EINSTEIN COLLEGE MEDICINE (US) 2026-03-04 EP disclosed
US-20250340532-A1 HETEROCYCLIC COMPOUND CCR4 INHIBITOR AND USER THEREOF XIZANG HAISCO PHARMACEUTICAL CO LTD (CN) 2025-11-06 US disclosed
US-12378259-B2 Light emitting device and polycyclic compound for the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-08-05 US disclosed
EP-4140974-B1 METHODS OF IRON CATALYZED C-H BOND AMINATION VERSITECH LTD (CN) 2025-05-14 EP disclosed
EP-4534534-A1 HETEROCYCLIC COMPOUND CCR4 INHIBITOR AND USER THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2025-04-09 EP disclosed
US-20250042849-A1 Process for the Preparation of Methyl 6-(2,4-Dichlorophenyl)-5-[4-[(3S)-1-(3-Fluoropropyl)Pyrrolidin-3-yl]Oxyphenyl]-8,9-Dihydro-7H-Benzo[7]Annulene-2-Carboxylate SANOFI (FR) 2025-02-06 US disclosed
EP-0044605-B1 FUNGICIDAL BIS-AZOLYL COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-02-12 EP disclosed
EP-0109606-B1 PROCESS FOR THE FORMYLATION OF ARYL HALIDES BAYER AG (DE) 1986-01-22 EP disclosed
EP-0158448-A2 Azolyl propanols IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-10-16 EP disclosed
US-4536344-A USING A PHOSPINE OR PHOSPHITE BAYER AKTIENGESELLSCHAFT (DE) 1985-08-20 US disclosed
US-4523019-A INTERMEDIATE FOR FUNGICIDE AND PLANT GROWTH REGULATOR IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-06-11 US disclosed
EP-0111658-A2 1,3-Dihalopropan-2-ols IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-06-27 EP disclosed
EP-0104734-A1 Triazole antifungal agents Pfizer Limited (GB) 1984-04-04 EP disclosed
EP-0099165-A1 Triazole and imidazole compounds, process for their preparation and their use as fungicides and plant growth regulators, and intermediates for their synthesis IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-25 EP disclosed
US-4416682-A 1,3-Bis(azolyl)propanols as fungicides and plant growth regulators IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-11-22 US disclosed