Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 18/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683730 | 0.89 | CCR5 (0.61) | CCR5 | |
| SCHEMBL7674740 | 0.81 | CCR5 (0.53) | CCR5 | |
| SCHEMBL7222341 | 0.77 | CCR5 (0.47) | CCR5POLBKMT2A | |
| SCHEMBL7681376 | 0.75 | CCR5 (0.60) | CCR5HPGD | |
| SCHEMBL5206027 | 0.72 | CCR5 (0.69) | CCR5 | |
| SCHEMBL7682539 | 0.70 | CCR5 (0.58) | CCR5 | |
| SCHEMBL5210129 | 0.70 | CCR5 (0.58) | CCR5 | |
| SCHEMBL5208341 | 0.70 | CCR5 (0.69) | CCR5 | |
| SCHEMBL5208404 | 0.69 | CCR5 (0.68) | CCR5 | |
| Iodide SCHEMBL7678648 | 0.69 | CCR5 (0.67) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413947-B1 | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |