Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxybate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7726627 | 0.90 | KDM4E (0.47) | LMNAKDM4EEPHX2ALDH1A1KMT2A | |
| 1,6-Hexanediol SCHEMBL15411480 | 0.88 | KDM4E (0.49) | LMNAKDM4EGPR84FFAR1FFAR4 | |
| Ethylene Glycol SCHEMBL15412415 | 0.86 | KDM4E (0.53) | LMNAKDM4EEPHX2ALDH1A1KMT2A | |
| Ethylene Glycol SCHEMBL15412379 | 0.86 | KDM4E (0.53) | LMNAKDM4EEPHX2ALDH1A1KMT2A | |
| SCHEMBL24004713 | 0.82 | KDM4E (0.61) | LMNAKDM4EEPHX2ALDH1A1KMT2A | |
| SCHEMBL75505 | 0.82 | KDM4E (0.61) | LMNAKDM4EEPHX2ALDH1A1KMT2A | |
| SCHEMBL6161898 | 0.82 | KDM4E (0.61) | LMNAKDM4EEPHX2ALDH1A1KMT2A | |
| SCHEMBL21705290 | 0.82 | KDM4E (0.61) | LMNAKDM4EEPHX2ALDH1A1KMT2A | |
| SCHEMBL900095 | 0.82 | KDM4E (0.61) | LMNAKDM4EEPHX2ALDH1A1KMT2A | |
| SCHEMBL5058845 | 0.82 | KDM4E (0.61) | LMNAKDM4EEPHX2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091216-A1 | Novel photoresist monomer having hydroxy group and carboxy group, copolymer thereof and photoresist composition using the same | HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) | 2002-07-11 | — | — | US | claimed |
| US-20020091216-A1 | Novel photoresist monomer having hydroxy group and carboxy group, copolymer thereof and photoresist composition using the same | HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) | 2002-07-11 | — | — | US | disclosed |