Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.54 |
| ▸ | RARA | P10276 | 11/20 | 0.54 |
| ▸ | RARG | P13631 | 15/20 | 0.42 |
| ▸ | RXRA | P19793 | 11/20 | 0.36 |
| ▸ | RXRB | P28702 | 9/20 | 0.36 |
| ▸ | RXRG | P48443 | 8/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674825 | 1.00 | RARB (0.54) | RARBRARARARGRXRARXRB | |
| SCHEMBL4431042 | 0.80 | RARB (0.55) | RARBRARARARGRXRA | |
| SCHEMBL6177290 | 0.80 | RARB (0.62) | RARBRARARARGRXRARXRB | |
| SCHEMBL7667562 | 0.78 | RARB (0.43) | RARBRARARARGRXRARXRB | |
| SCHEMBL7667567 | 0.76 | RXRA (0.46) | RARBRARARARGRXRARXRB | |
| SCHEMBL7669825 | 0.75 | RARB (0.50) | RARBRARARARGRXRA | |
| SCHEMBL7671013 | 0.75 | RARB (0.50) | RARBRARARARGRXRA | |
| SCHEMBL22411137 | 0.73 | RARB (0.55) | RARBRARARARG | |
| SCHEMBL6175867 | 0.72 | RARB (0.50) | RARBRARARARG | |
| SCHEMBL24410709 | 0.72 | RXRA (0.39) | RARBRARARARGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420363-B1 | Mono- or polyenic carboxylic acid derivatives | EISAI CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| US-6291508-B1 | POTENT ABILITY TO BIND TO RETINOIC ACID RECEPTORS THUS USEFUL IN TREATING PSORIASIS AND RHEUMATOID ARTHRITIS. | EISAI CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| US-6133283-A | Mono- or polyenic carboxylic acid derivatives | EISAI CO., LTD. (JP) | 2000-10-17 | — | — | US | disclosed |
| US-5977125-A | Mono-or polyenic carboxylic acid derivatives | EISAI CO., LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0790228-A1 | MONO- OR POLYENIC CARBOXYLIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1997-08-20 | — | — | EP | disclosed |