SCHEMBL7674832

CCCCC1(CCCC)NS(=O)(=O)c2ccc(N(C)C)cc2[C@@H](c2cccc([N+](=O)[O-])c2)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	SLC10A2	Q12908	20/20	1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7670967	1.00	SLC10A2 (1.00)	SLC10A2
SCHEMBL7850982	1.00	SLC10A2 (1.00)	SLC10A2
SCHEMBL7673034	0.87	SLC10A2 (1.00)	SLC10A2
SCHEMBL7850994	0.86	SLC10A2 (1.00)	SLC10A2
SCHEMBL348804	0.83	SLC10A2 (0.76)	SLC10A2
SCHEMBL7849977	0.83	SLC10A2 (1.00)	SLC10A2
SCHEMBL12196435	0.82	SLC10A2 (0.76)	SLC10A2
SCHEMBL12196433	0.82	SLC10A2 (0.76)	SLC10A2
SCHEMBL12196437	0.82	SLC10A2 (0.76)	SLC10A2
SCHEMBL12196436	0.82	SLC10A2 (0.76)	SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
JP-2002536440-A	—	—	2002-10-29	—	—	JP	claimed
EP-1155007-A2	1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES	G.D. Searle LLC (US)	2001-11-21	—	—	EP	claimed
WO-2000047568-A2	1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES	G.D. SEARLE LLC (US)	2000-08-17	—	—	WO	claimed
EP-1155007-A2	1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES	G.D. Searle LLC (US)	2001-11-21	—	—	EP	disclosed
WO-2000047568-A2	1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES	G.D. SEARLE LLC (US)	2000-08-17	—	—	WO	disclosed