Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12806081 | 0.86 | GABRA1 (0.64) | GABRA1GABRB2MEN1KMT2AIDO1 | |
| SCHEMBL31200741 | 0.86 | GABRA1 (0.64) | GABRA1GABRB2MEN1KMT2AIDO1 | |
| SCHEMBL9211153 | 0.82 | IDO1 (0.42) | GABRA1GABRB2MEN1KMT2AIDO1 | |
| SCHEMBL7674886 | 0.80 | PDE4A (0.44) | GABRA1GABRB2MEN1KMT2AIDO1 | |
| SCHEMBL31614197 | 0.80 | IDO1 (0.41) | GABRA1GABRB2MEN1KMT2AIDO1 | |
| SCHEMBL27761667 | 0.80 | TAAR1 (0.50) | GABRA1GABRB2MEN1KMT2AIDO1 | |
| SCHEMBL83159 | 0.79 | IDO1 (0.57) | IDO1TAAR1KDM4EALDH1A1CA12 | |
| SCHEMBL29071153 | 0.78 | HSD17B10 (0.50) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1501174 | 0.78 | CA1 (0.58) | KDM4EALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL95872 | 0.78 | CA12 (0.53) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |