Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 6/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673150 | 1.00 | RAB9A (0.36) | RAB9ASMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL7673146 | 1.00 | RAB9A (0.36) | RAB9ASMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL7665577 | 0.93 | SMN1; SMN2 (0.35) | RAB9ASMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL7664612 | 0.93 | SMN1; SMN2 (0.35) | RAB9ASMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL7664617 | 0.93 | SMN1; SMN2 (0.35) | RAB9ASMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL6566910 | 0.92 | KDM4E (0.36) | RAB9ASMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL6567869 | 0.92 | KDM4E (0.36) | RAB9ASMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL6566914 | 0.92 | KDM4E (0.36) | RAB9ASMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL7673576 | 0.91 | RAB9A (0.36) | RAB9ASMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL7673204 | 0.91 | RAB9A (0.36) | RAB9ASMN1; SMN2KDM4ELMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486183-B1 | Antivirals | MEDIVIR AB (SE) | 2002-11-26 | — | — | US | disclosed |