Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664217 | 0.91 | SIRT2 (0.42) | SIRT2CYP11B1CYP11B2KIF11LOXL2 | |
| SCHEMBL7663646 | 0.89 | L3MBTL1 (0.45) | SIRT2CYP11B1CYP11B2ENPP2MAOB | |
| SCHEMBL5688738 | 0.86 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2ENPP2 | |
| SCHEMBL1924923 | 0.85 | SIRT2 (0.45) | SIRT2CYP11B1CYP11B2ENPP2 | |
| SCHEMBL7668533 | 0.84 | SIRT2 (0.43) | SIRT2CYP11B1CYP11B2 | |
| SCHEMBL7666301 | 0.83 | PLA2G10 (0.50) | SIRT2KIF11 | |
| SCHEMBL2787690 | 0.82 | CYP19A1 (0.40) | SIRT2CYP11B1CYP11B2KIF11MAOB | |
| SCHEMBL7673104 | 0.80 | POLB (0.41) | SIRT2 | |
| SCHEMBL2035093 | 0.79 | SIRT2 (0.49) | SIRT2CYP11B1CYP11B2LOXL2TAAR1 | |
| SCHEMBL7666260 | 0.77 | SIRT2 (0.43) | SIRT2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407132-B1 | ANTIHISTAMINES, ANTIALLERGENS, ANTIASTHMATICS, ANTICONVULSANTS, AND ANTIDEPRESSANTS; SKIN RASH TREATMENT | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-06-18 | — | — | US | disclosed |