Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | CBLB | Q13191 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674466 | 0.88 | HDAC1 (0.53) | BCAT1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL7673862 | 0.85 | RAB9A (0.49) | CBLBKDM4EMAPTNPC1RAB9A | |
| SCHEMBL7666423 | 0.84 | RAB9A (0.48) | KDRKDM4EMAPTNPC1RAB9A | |
| SCHEMBL7670423 | 0.82 | RAB9A (0.49) | ABCG2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL5093025 | 0.79 | IKBKB (0.57) | KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7666491 | 0.79 | MAPT (0.43) | KDM4EMAPTNPC1RAB9AMEN1 | |
| SCHEMBL7666511 | 0.78 | MAPT (0.51) | KDM4EMAPTNPC1RAB9AMEN1 | |
| SCHEMBL7668949 | 0.78 | MAPT (0.42) | NTRK1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7670178 | 0.78 | MAPT (0.41) | KDM4EMAPTNPC1RAB9AMEN1 | |
| SCHEMBL7676538 | 0.78 | PARP1 (0.49) | KDRKDM4EMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | claimed |