Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675407 | 0.81 | MAPK1 (0.45) | MAPK1GFERKDM4EMAPTIKBKB | |
| SCHEMBL7675292 | 0.80 | MAPK1 (0.56) | MAPK1GFERMAPK10 | |
| SCHEMBL7674136 | 0.80 | MAPK1 (0.43) | MAPK1GFERKDM4EMAPTMAPK10 | |
| SCHEMBL5093025 | 0.78 | IKBKB (0.57) | MAPK1GFERKDM4EMAPTIKBKB | |
| SCHEMBL7674134 | 0.78 | MAPK1 (0.44) | MAPK1GFERKDM4EMAPTIKBKB | |
| SCHEMBL7670987 | 0.76 | MAPK1 (0.45) | MAPK1GFERKDM4EMAPTIKBKB | |
| SCHEMBL7005038 | 0.73 | HDAC1 (0.46) | MAPK1GFERKDM4EMAPTIKBKB | |
| SCHEMBL7672756 | 0.73 | KDM4E (0.40) | MAPK1GFERKDM4EMAPTMAPK10 | |
| SCHEMBL7676277 | 0.72 | KDM4E (0.50) | MAPK1GFERP2RX7KDM4EMAPT | |
| SCHEMBL7675378 | 0.72 | KDM4E (0.49) | MAPK1GFERKDM4EMAPTIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | claimed |