Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674134 | 0.84 | MAPK1 (0.44) | MAPK1GFERKDM4EMAPTMEN1 | |
| SCHEMBL7675404 | 0.80 | MAPK1 (0.53) | MAPK1GFERKDM4EMAPTHTT | |
| SCHEMBL5093025 | 0.80 | IKBKB (0.57) | MAPK1GFERKDM4EMAPTMEN1 | |
| SCHEMBL7668077 | 0.78 | MAPT (0.41) | MAPK1GFERKDM4EMAPTMEN1 | |
| SCHEMBL7005038 | 0.77 | HDAC1 (0.46) | MAPK1GFERKDM4EMAPTALDH1A1 | |
| SCHEMBL6995431 | 0.77 | GPR139 (0.49) | KDM4EMAPTMEN1HPGDKMT2A | |
| SCHEMBL7672756 | 0.75 | KDM4E (0.40) | MAPK1GFERKDM4EMAPTMEN1 | |
| SCHEMBL7672584 | 0.74 | ALOX15 (0.45) | MEN1KMT2AALDH1A1ALOX15HSD17B10 | |
| SCHEMBL7676277 | 0.74 | KDM4E (0.50) | MAPK1GFERKDM4EMAPTMEN1 | |
| SCHEMBL7003097 | 0.74 | MAPK1 (0.65) | MAPK1GFERKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | claimed |