SCHEMBL7675583

SCHEMBL7675583

NC(=O)C=C(C(N)=O)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
FGFR4 P22455 1/20 0.39
LDHA P00338 2/20 0.35
LDHB P07195 1/20 0.35
LMNA P02545 2/20 0.33
BLM P54132 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
OR51E2 Q9H255 1/20 0.33
CA2 P00918 1/20 0.33
CYP3A4 P08684 1/20 0.33
NFKB1 P19838 1/20 0.33
CA5A P35218 1/20 0.33
PMP22 Q01453 1/20 0.33
CA9 Q16790 1/20 0.33
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11029233 0.84 LDHA (0.44) ALDH1A1TSHRFGFR4LDHALDHB
SCHEMBL11532314 0.84 LDHA (0.44) ALDH1A1TSHRFGFR4LDHALDHB
SCHEMBL11029237 0.84 LDHA (0.44) ALDH1A1TSHRFGFR4LDHALDHB
SCHEMBL9227817 0.78 GLRA1 (0.30) OR51E2POLB
SCHEMBL9227802 0.78 GLRA1 (0.30) OR51E2POLB
SCHEMBL9245441 0.76 LDHA (0.41) ALDH1A1TSHRFGFR4LDHALDHB
SCHEMBL28929335 0.71
SCHEMBL20913029 0.71
SCHEMBL20913028 0.71
SCHEMBL3189718 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108430442-A It include the method for handling keratin fiber using the composition comprising urea or derivatives thereof, polyalcohol and amodimethicone 欧莱雅 2018-08-21 CN claimed
CN-108430442-A It include the method for handling keratin fiber using the composition comprising urea or derivatives thereof, polyalcohol and amodimethicone 欧莱雅 2018-08-21 CN disclosed
US-6414013-B1 KINASE INHIBITORS; ANTICANCER AGENTS PHARMACIA & UPJOHN S.P.A. (IT) 2002-07-02 US disclosed