Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | F12 | P00748 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15842719 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1NPSR1POLBMAPT | |
| SCHEMBL28812863 | 0.80 | KDM4E (0.77) | KDM4EALDH1A1NPSR1POLBMAPT | |
| SCHEMBL15733005 | 0.79 | KDM4E (0.79) | KDM4EALDH1A1NPSR1POLBMAPT | |
| SCHEMBL7682058 | 0.77 | KDM4E (0.71) | KDM4EALDH1A1NPSR1POLBMAPT | |
| SCHEMBL6084594 | 0.76 | KDM4E (0.80) | KDM4EALDH1A1NPSR1POLBMAPT | |
| SCHEMBL7675591 | 0.75 | F12 (0.63) | KDM4EALDH1A1NPSR1POLBMAPT | |
| SCHEMBL76086 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1NPSR1POLBMAPT | |
| SCHEMBL7682509 | 0.74 | KDM4E (0.76) | KDM4EALDH1A1NPSR1POLBMAPT | |
| SCHEMBL15733119 | 0.74 | MEN1 (0.72) | KDM4EALDH1A1NPSR1POLBMAPT | |
| SCHEMBL7681874 | 0.72 | KDM4E (0.65) | KDM4EALDH1A1NPSR1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |