Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | F12 | P00748 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675585 | 0.88 | MEN1 (0.51) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL15733119 | 0.87 | MEN1 (0.72) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL1221234 | 0.75 | LMNA (0.57) | KDM4EALDH1A1POLBMAPTHSD17B10 | |
| SCHEMBL7681946 | 0.74 | MEN1 (0.67) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL15842719 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL5998660 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL7675591 | 0.73 | F12 (0.63) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL28812863 | 0.73 | KDM4E (0.77) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL7675587 | 0.72 | KDM4E (0.67) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL7682058 | 0.72 | KDM4E (0.71) | KDM4EALDH1A1POLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |