Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | EIF4E | P06730 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677284 | 0.89 | MAPT (0.51) | MEN1KMT2AEIF4EMAPTSMN1; SMN2 | |
| SCHEMBL7669303 | 0.88 | EIF4E (0.50) | MEN1KMT2AEIF4EMAPTSMN1; SMN2 | |
| SCHEMBL7677249 | 0.87 | MAPT (0.48) | MEN1KMT2AEIF4EMAPTSMN1; SMN2 | |
| SCHEMBL7672520 | 0.86 | EIF4E (0.52) | MEN1KMT2AEIF4EMAPTSMN1; SMN2 | |
| SCHEMBL7535129 | 0.84 | EIF4E (0.47) | MEN1KMT2AEIF4EMAPTSMN1; SMN2 | |
| SCHEMBL7676398 | 0.79 | MAPT (0.62) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL19196240 | 0.77 | CSNK2A1 (0.64) | MEN1KMT2AEIF4EMAPTSMN1; SMN2 | |
| SCHEMBL7671981 | 0.75 | MAPT (0.62) | MEN1KMT2AEIF4EMAPTSMN1; SMN2 | |
| SCHEMBL7596877 | 0.74 | ALDH1A1 (0.63) | MEN1KMT2ATDP1ALDH1A1PKM | |
| SCHEMBL3149347 | 0.74 | ALDH1A1 (0.63) | MEN1KMT2ATDP1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380187-B2 | FUNGICIDES | YU DINGWEI TIM (US) | 2002-04-30 | — | — | US | disclosed |
| US-6281217-B2 | ANTIFUNGAL ACTIVITY AGAINST A VARIETY OF FUNGI INCLUDING STRAINS WHICH HAVE PROVEN TO BE RESISTANT TO TREATMENT WITH KNOWN ANTIFUNGAL AGENTS SUCH AS FLUCONAZOLE. | YU DINGWEI TIM (US) | 2001-08-28 | — | — | US | disclosed |
| US-6156776-A | Diaryl substituted thiazoles useful in the treatment of fungal infections | YU DINGWEI TIM (US) | 2000-12-05 | — | — | US | disclosed |