Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.59 |
| ▸ | MMP8 | P22894 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677247 | 0.88 | MMP9 (0.74) | MMP9MMP8POLBKDM4EAPAF1 | |
| SCHEMBL7674968 | 0.82 | MMP9 (0.64) | MMP9MMP8POLBKDM4EAPAF1 | |
| SCHEMBL7670547 | 0.82 | MMP9 (0.66) | MMP9MMP8POLBKDM4EAPAF1 | |
| SCHEMBL7678175 | 0.81 | MMP9 (0.62) | MMP9MMP8POLBKDM4EAPAF1 | |
| SCHEMBL7678213 | 0.81 | POLB (0.57) | MMP9MMP8POLBKDM4EAPAF1 | |
| SCHEMBL7854107 | 0.80 | KDM4E (0.70) | MMP9MMP8POLBKDM4EAPAF1 | |
| SCHEMBL7669468 | 0.80 | MMP9 (0.58) | MMP9MMP8POLBKDM4EAPAF1 | |
| SCHEMBL7671885 | 0.79 | CYP3A4 (0.69) | MMP9MMP8POLBKDM4EAPAF1 | |
| SCHEMBL7675824 | 0.78 | MMP9 (0.58) | MMP9MMP8POLBKDM4EAPAF1 | |
| SCHEMBL7673192 | 0.78 | POLB (0.63) | MMP9MMP8POLBKDM4EAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |