Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 20/20 | 0.54 |
| ▸ | CDK4 | P11802 | 11/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675293 | 0.82 | CDK2 (0.56) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7679995 | 0.82 | CDK2 (0.47) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7679992 | 0.82 | CDK2 (0.47) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7676570 | 0.79 | CDK2 (0.55) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7681461 | 0.78 | CDK2 (0.40) | CDK2CDK4CCNE1 | |
| SCHEMBL7676812 | 0.76 | CDK2 (0.57) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7683359 | 0.76 | CDK2 (0.59) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7676292 | 0.75 | CDK2 (0.56) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7689371 | 0.73 | CDK2 (0.57) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7673429 | 0.72 | CDK2 (0.56) | CDK2CDK4CDK1CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |