Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 14/20 | 0.49 |
| ▸ | CDK4 | P11802 | 9/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676564 | 1.00 | CDK2 (0.49) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7681318 | 0.81 | CDK2 (0.53) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7681314 | 0.81 | CDK2 (0.53) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7680600 | 0.80 | CDK2 (0.50) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7680602 | 0.80 | CDK2 (0.50) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7679992 | 0.79 | CDK2 (0.47) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7679995 | 0.79 | CDK2 (0.47) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7693720 | 0.70 | CDK2 (0.40) | CDK2CDK4HTR6CDK1CCNB1 | |
| SCHEMBL7693721 | 0.70 | CDK2 (0.40) | CDK2CDK4HTR6CDK1CCNB1 | |
| SCHEMBL7676570 | 0.69 | CDK2 (0.55) | CDK2CDK4CDK1CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |