Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 16/20 | 0.50 |
| ▸ | CDK4 | P11802 | 9/20 | 0.50 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680600 | 1.00 | CDK2 (0.50) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7676568 | 0.80 | CDK2 (0.49) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7676564 | 0.80 | CDK2 (0.49) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7681314 | 0.80 | CDK2 (0.53) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7681318 | 0.80 | CDK2 (0.53) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7679992 | 0.77 | CDK2 (0.47) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7679995 | 0.77 | CDK2 (0.47) | CDK2CDK4PDE4APDE4BPDE4C | |
| SCHEMBL7681605 | 0.72 | CDK2 (0.39) | CDK2CDK4HTR6CDK1CCNB1 | |
| Benzene SCHEMBL28266121 | 0.66 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL247446 | 0.66 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |