Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 18/20 | 0.50 |
| ▸ | CDK4 | P11802 | 9/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681390 | 0.93 | CDK2 (0.46) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7682123 | 0.91 | CDK2 (0.43) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7675122 | 0.90 | CDK2 (0.43) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7676510 | 0.90 | CDK2 (0.47) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7679500 | 0.87 | CDK2 (0.43) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7676916 | 0.86 | CDK2 (0.44) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7682045 | 0.85 | CDK2 (0.43) | CDK2CDK4 | |
| SCHEMBL7676621 | 0.85 | CDK2 (0.43) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7676606 | 0.85 | CDK2 (0.43) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7679621 | 0.85 | CDK2 (0.43) | CDK2CDK4ABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |