Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 6/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 8/20 | 0.38 |
| ▸ | AKT2 | P31751 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676827 | 0.96 | ABCC9 (0.38) | CDK2CDK4CSNK1DCSNK1EUSP7 | |
| SCHEMBL7679500 | 0.94 | CDK2 (0.43) | CDK2CDK4USP7AKT1AKT2 | |
| SCHEMBL7676353 | 0.91 | CDK2 (0.42) | CDK2CDK4CSNK1DCSNK1EUSP7 | |
| SCHEMBL7680034 | 0.91 | CDK2 (0.40) | CDK2CDK4USP7AKT1AKT2 | |
| SCHEMBL7674349 | 0.91 | TRPV1 (0.40) | CDK2CDK4USP7 | |
| SCHEMBL7677596 | 0.91 | CDK2 (0.41) | CDK2CDK4USP7AKT1AKT2 | |
| SCHEMBL7679621 | 0.89 | CDK2 (0.43) | CDK2CDK4USP7AKT1AKT2 | |
| SCHEMBL7675092 | 0.89 | AKT1 (0.47) | CDK2CDK4USP7AKT1AKT2 | |
| SCHEMBL7676606 | 0.89 | CDK2 (0.43) | CDK2CDK4MAPT | |
| SCHEMBL7673955 | 0.88 | NPC1 (0.42) | CDK2USP7AKT1AKT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |