Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 3/20 | 0.40 |
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983953 | 0.86 | CCNT1 (0.43) | CCNT1CDK9CDK2CDK4CCND1 | |
| SCHEMBL6976153 | 0.86 | PIM1 (0.40) | CCNT1CDK9CDK2CCNE2CDK4 | |
| SCHEMBL6983267 | 0.85 | CCNE2 (0.45) | CCNT1CDK9CDK2CCNE2CDK4 | |
| Hydrochloric Acid SCHEMBL6975831 | 0.85 | PIM1 (0.39) | CCNT1CDK9CDK2CCNE2CDK4 | |
| SCHEMBL6981727 | 0.85 | CCNT1 (0.53) | CCNT1CDK9CDK2PIM1CCNA2 | |
| Dimethylamine SCHEMBL6976140 | 0.84 | CCNT1 (0.41) | CCNT1CDK9CDK2PIM1CCNA2 | |
| SCHEMBL6980550 | 0.83 | PRKACA (0.46) | CCNT1CDK9CDK2CDK4CCND1 | |
| SCHEMBL6983101 | 0.83 | CCNT1 (0.44) | CCNT1CDK9CDK2PIM1CCNA2 | |
| SCHEMBL6977406 | 0.83 | CAMK2D (0.56) | CCNT1CDK9PIM1CAMK2DPRKACA | |
| SCHEMBL6975973 | 0.82 | CAMK2D (0.53) | CCNT1CDK9CDK2PIM1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | claimed |