Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MITF | O75030 | 3/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 3/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015809 | 0.85 | KMT2A (0.64) | KDRKMT2AMITFGSK3AGSK3B | |
| SCHEMBL6015821 | 0.85 | KMT2A (0.64) | KDRKMT2AMITFGSK3AGSK3B | |
| SCHEMBL6016074 | 0.80 | KDR (0.55) | KDRKMT2AGSK3AGSK3BALDH1A1 | |
| SCHEMBL6016071 | 0.80 | KDR (0.55) | KDRKMT2AGSK3AGSK3BALDH1A1 | |
| SCHEMBL6015657 | 0.79 | KDR (0.73) | KDRKMT2AMITFGSK3AGSK3B | |
| SCHEMBL6015653 | 0.79 | KDR (0.73) | KDRKMT2AMITFGSK3AGSK3B | |
| SCHEMBL6015991 | 0.73 | KDR (0.59) | KDRKMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6015983 | 0.73 | KDR (0.59) | KDRKMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1247740 | 0.72 | HPGD (0.46) | GSK3BRAB9AMAPTNPC1 | |
| SCHEMBL1247737 | 0.72 | HPGD (0.46) | GSK3BRAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |