Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.64 |
| ▸ | MITF | O75030 | 4/20 | 0.64 |
| ▸ | GSK3A | P49840 | 2/20 | 0.64 |
| ▸ | GSK3B | P49841 | 2/20 | 0.64 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | RAD52 | P43351 | 3/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015821 | 1.00 | KMT2A (0.64) | KMT2AMITFGSK3AGSK3BKDR | |
| SCHEMBL7677330 | 0.85 | KDR (0.64) | KMT2AMITFGSK3AGSK3BKDR | |
| SCHEMBL6016071 | 0.80 | KDR (0.55) | KMT2AGSK3AGSK3BKDRCDK5 | |
| SCHEMBL6016074 | 0.80 | KDR (0.55) | KMT2AGSK3AGSK3BKDRCDK5 | |
| SCHEMBL6015653 | 0.74 | KDR (0.73) | KMT2AMITFGSK3AGSK3BKDR | |
| SCHEMBL6015657 | 0.74 | KDR (0.73) | KMT2AMITFGSK3AGSK3BKDR | |
| SCHEMBL6015983 | 0.73 | KDR (0.59) | KMT2AKDRCDK5PIM1NPC1 | |
| SCHEMBL6015991 | 0.73 | KDR (0.59) | KMT2AKDRCDK5PIM1NPC1 | |
| SCHEMBL6016042 | 0.69 | KDR (0.51) | KMT2AKDRCDK5NPC1RAB9A | |
| SCHEMBL6016045 | 0.69 | KDR (0.51) | KMT2AKDRCDK5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |