Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768533 | 1.00 | HRH3 (0.41) | HRH3DRD2NPC1HTR1AMTOR | |
| SCHEMBL768953 | 0.99 | HRH3 (0.42) | HRH3DRD2NPC1HTR1AMTOR | |
| SCHEMBL768640 | 0.93 | CHRM3 (0.45) | HRH3PRCPSLC2A1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL768805 | 0.93 | CHRM3 (0.45) | HRH3PRCPSLC2A1CHRM3CHRM2 | |
| SCHEMBL768103 | 0.92 | HRH3 (0.41) | HRH3DRD2NPC1HTR1AMTOR | |
| SCHEMBL768619 | 0.91 | HRH3 (0.40) | HRH3DRD2NPC1HTR1AMTOR | |
| SCHEMBL768743 | 0.89 | HRH3 (0.37) | HRH3PRCPSLC2A1CHRM3CHRM2 | |
| SCHEMBL768439 | 0.88 | CHRM2 (0.39) | HRH3SLC2A1CHRM3CHRM2 | |
| SCHEMBL768735 | 0.88 | HRH3 (0.40) | HRH3CHRM3CHRM2 | |
| SCHEMBL769138 | 0.88 | HRH3 (0.41) | HRH3DRD2PRCPHTR7HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | CHRM3, CHRM2, TACR2 | HRH3 96/4885DRD2 294/4885NPC1 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.