Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769194 | 0.91 | HRH3 (0.39) | HRH3MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL768953 | 0.89 | HRH3 (0.42) | HRH3MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL767767 | 0.88 | HRH3 (0.41) | HRH3CHRM3CHRM2 | |
| SCHEMBL768533 | 0.88 | HRH3 (0.41) | HRH3CHRM3CHRM2 | |
| SCHEMBL768640 | 0.83 | CHRM3 (0.45) | HRH3CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL768805 | 0.83 | CHRM3 (0.45) | HRH3CHRM3CHRM2 | |
| SCHEMBL769138 | 0.83 | HRH3 (0.41) | HRH3MEN1KMT2AALDH1A1CHRM3 | |
| SCHEMBL769112 | 0.82 | HRH3 (0.40) | HRH3ALDH1A1CHRM3POLBCHRM2 | |
| SCHEMBL768103 | 0.82 | HRH3 (0.41) | HRH3CHRM3CHRM2 | |
| SCHEMBL768619 | 0.82 | HRH3 (0.40) | HRH3MEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | CHRM3, CHRM2, TACR2 | HRH3 96/4885MEN1 1905/4885KMT2A 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.