Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 19/20 | 0.59 |
| ▸ | WDR77 | Q9BQA1 | 19/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677794 | 1.00 | PRMT5 (0.59) | PRMT5WDR77MEN1PKMKMT2A | |
| SCHEMBL6549677 | 0.84 | ABCB1 (0.52) | — | |
| SCHEMBL6549673 | 0.84 | ABCB1 (0.52) | — | |
| Hydrochloric Acid SCHEMBL6549702 | 0.81 | PRMT5 (0.55) | PRMT5WDR77MEN1PKMKMT2A | |
| SCHEMBL7683852 | 0.79 | KDM4E (0.56) | PRMT5WDR77MEN1KMT2A | |
| SCHEMBL15833548 | 0.74 | PRMT5 (1.00) | PRMT5WDR77MEN1PKMKMT2A | |
| SCHEMBL15943991 | 0.73 | PRMT5 (1.00) | PRMT5WDR77MEN1PKMKMT2A | |
| SCHEMBL6548351 | 0.72 | ABCB1 (0.67) | MEN1KMT2A | |
| SCHEMBL22545807 | 0.72 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL22545816 | 0.72 | PRMT5 (1.00) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500823-B1 | ENERGY DEFICIENCY OF THE CELL CAUSED BY PARP INHIBITION, IN DIABETES COMPLICATIONS, IN OXYGEN DEFICIENT STATUS OF THE HEART AND BRAIN, IN NEURODEGENERATIVE DISEASES, IN THE TREATMENT OF AUTOIMMUNE AND/OR VIRAL DISEASES | N-GENE RESEARCH LABORATORIES, INC. | 2002-12-31 | — | — | US | claimed |