Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.67 |
| ▸ | MMP2 | P08253 | 2/20 | 0.67 |
| ▸ | MMP8 | P22894 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TACR3 | P29371 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892616 | 0.83 | KMT2A (0.83) | MMP9MMP2MMP8MAPTMEN1 | |
| SCHEMBL7853492 | 0.81 | MAPT (0.62) | MMP9MMP2MMP8MAPTMEN1 | |
| SCHEMBL7671885 | 0.81 | CYP3A4 (0.69) | MMP9MMP2MMP8MAPTMEN1 | |
| SCHEMBL7618661 | 0.81 | NLN (0.70) | MMP9MMP2MMP8MAPTMEN1 | |
| SCHEMBL7678071 | 0.81 | KDM4E (0.67) | MMP9MMP8MAPTMEN1KMT2A | |
| SCHEMBL8829877 | 0.80 | MEN1 (0.55) | MMP9MMP2MMP8MAPTMEN1 | |
| SCHEMBL17017538 | 0.79 | POLB (0.69) | MMP9MMP8MAPTMEN1KMT2A | |
| SCHEMBL7672636 | 0.79 | KDM4E (0.65) | MMP9MMP8MAPTMEN1KMT2A | |
| SCHEMBL7674947 | 0.79 | POLB (0.82) | MMP9MMP2MMP8MAPTMEN1 | |
| SCHEMBL7671378 | 0.79 | MAPT (0.65) | MMP9MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |