Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PRCP | P42785 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295913 | 0.82 | PRCP (0.56) | HTR6ADRA2BADRA2CADRA1ADRD2 | |
| SCHEMBL19677006 | 0.79 | HTR6 (0.49) | HTR6ADRA2BADRA2CADRA1ADRD2 | |
| SCHEMBL21194619 | 0.79 | HTR6 (0.53) | HTR6ADRA2BADRA2CADRA1ADRD2 | |
| SCHEMBL29462285 | 0.79 | HTR6 (0.53) | HTR6ADRA2BADRA2CADRA1ADRD2 | |
| SCHEMBL9636734 | 0.79 | HTR6 (0.49) | HTR6ADRA2BADRA2CADRA1ADRD2 | |
| SCHEMBL18709273 | 0.79 | HTR6 (0.49) | HTR6ADRA2BADRA2CADRA1ADRD2 | |
| SCHEMBL14015841 | 0.78 | HTR6 (0.54) | HTR6ADRA2BADRA2CADRA1AHTR2A | |
| SCHEMBL1125363 | 0.78 | HTR6 (0.54) | HTR6ADRA2BADRA2CADRA1AHTR2A | |
| SCHEMBL29511517 | 0.78 | HTR6 (0.54) | HTR6ADRA2BADRA2CADRA1AHTR2A | |
| SCHEMBL27488330 | 0.76 | HTR6 (0.56) | HTR6ADRA2BADRA2CADRA1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342612-B1 | FRAGRANCES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-01-29 | — | — | US | claimed |
| US-6362141-B1 | ORGANOLEPTIC; PERFUMES, COSMETICS, CLEANING COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-26 | — | — | US | disclosed |
| US-6342612-B1 | FRAGRANCES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-01-29 | — | — | US | disclosed |